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Grazia Graziani Selected Research

N3-methyladenine

2/2005N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.
7/2002Pharmacological strategies to increase the antitumor activity of methylating agents.

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Grazia Graziani Research Topics

Disease

59Neoplasms (Cancer)
01/2023 - 02/2000
28Melanoma (Melanoma, Malignant)
01/2023 - 07/2002
9Glioblastoma (Glioblastoma Multiforme)
11/2020 - 10/2002
7Glioma (Gliomas)
01/2021 - 07/2002
6Colonic Neoplasms (Colon Cancer)
07/2013 - 04/2002
5Brain Neoplasms (Brain Tumor)
03/2020 - 03/2004
4Breast Neoplasms (Breast Cancer)
12/2018 - 04/2002
3Colorectal Neoplasms (Colorectal Cancer)
06/2021 - 08/2006
3Leukemia
01/2021 - 02/2005
3Prostatic Neoplasms (Prostate Cancer)
11/2018 - 05/2007
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 03/2015
3Carcinoma (Carcinomatosis)
07/2013 - 08/2006
3Genomic Instability
02/2006 - 02/2000
3Lymphoma (Lymphomas)
02/2005 - 03/2002
2Neuralgia (Stump Neuralgia)
04/2024 - 10/2021
2Neurodegenerative Diseases (Neurodegenerative Disease)
02/2024 - 12/2023
2Acute Promyelocytic Leukemia
01/2021 - 05/2017
2Pathologic Neovascularization
02/2020 - 01/2020
2Neoplasm Metastasis (Metastasis)
02/2020 - 12/2005
2Carcinogenesis
02/2017 - 05/2007
2Tuberculosis (Tuberculoses)
01/2011 - 03/2007
2Inflammation (Inflammations)
06/2008 - 08/2006
2Experimental Melanoma
12/2005 - 02/2005
2Necrosis
02/2005 - 02/2002
2Adenocarcinoma
07/2003 - 03/2002
1Glaucoma
12/2023
1Wounds and Injuries (Trauma)
12/2023

Drug/Important Bio-Agent (IBA)

19Poly(ADP-ribose) Polymerase InhibitorsIBA
11/2022 - 03/2002
16Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2024 - 03/2004
16Temozolomide (Temodar)FDA LinkGeneric
03/2014 - 03/2002
15Monoclonal AntibodiesIBA
04/2024 - 01/2012
12Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2022 - 01/2003
11Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
11/2022 - 01/2011
10Antineoplastic Agents (Antineoplastics)IBA
01/2022 - 03/2002
8D16F7IBA
11/2022 - 11/2016
8LigandsIBA
02/2020 - 01/2015
7Immune Checkpoint InhibitorsIBA
11/2022 - 01/2018
7Proteins (Proteins, Gene)FDA Link
11/2020 - 02/2006
6AntigensIBA
01/2022 - 04/2002
6Telomerase (Telomerase Reverse Transcriptase)IBA
01/2021 - 02/2000
6Poly (ADP-Ribose) Polymerase-1IBA
03/2014 - 03/2002
5Neuropilin-1IBA
01/2023 - 01/2015
5Placenta Growth FactorIBA
11/2022 - 01/2011
4DNA (Deoxyribonucleic Acid)IBA
11/2022 - 03/2002
4IntegrinsIBA
11/2022 - 04/2008
4IpilimumabIBA
01/2022 - 01/2012
4Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
10/2021 - 11/2016
4Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2020 - 09/2017
4olaparibIBA
09/2019 - 03/2015
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2018 - 05/2007
4EnzymesIBA
11/2017 - 01/2003
3platelet-derived growth factor C (PDGF-C)IBA
01/2023 - 12/2013
3Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022 - 01/2020
3Vascular Endothelial Growth Factor BIBA
02/2020 - 10/2018
3Bevacizumab (Avastin)FDA Link
01/2020 - 04/2016
3A-Form DNA (A-DNA)IBA
11/2017 - 03/2002
3Dacarbazine (DIC)FDA LinkGeneric
05/2011 - 03/2004
3StaurosporineIBA
11/2010 - 04/2002
3Carcinoembryonic AntigenIBA
11/2010 - 04/2002
3O-(6)-methylguanineIBA
01/2009 - 07/2002
3GPI 15427IBA
08/2006 - 11/2003
2Vascular Endothelial Growth FactorsIBA
02/2024 - 02/2020
2Nerve Growth Factors (Neurotrophins)IBA
12/2023 - 01/2021
2NivolumabIBA
01/2022 - 01/2022
2Programmed Cell Death 1 ReceptorIBA
01/2022 - 01/2022
2Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2021 - 07/2013
2Ascorbic Acid (Vitamin C)FDA LinkGeneric
03/2021 - 01/2021
2ErbB Receptors (EGF Receptor)IBA
01/2021 - 12/2016
2Arsenic Trioxide (Trisenox)FDA Link
01/2021 - 05/2017
2gamma-glutamylaminomethylsulfonic acid (GAMS)IBA
11/2020 - 01/2017
2VemurafenibIBA
01/2020 - 05/2015
2Glutathione Transferase (Glutathione S-Transferase)IBA
01/2019 - 05/2011
2MC3181IBA
01/2019 - 05/2015
2Platinum Compounds (Compounds, Platinum)IBA
12/2018 - 07/2013
2Transcription Factors (Transcription Factor)IBA
09/2017 - 01/2011
2JNK Mitogen-Activated Protein KinasesIBA
05/2015 - 05/2011
2Metalloproteases (Metalloproteinases)IBA
03/2015 - 01/2015
2CilengitideIBA
03/2015 - 04/2008
2Complementary DNA (cDNA)IBA
07/2013 - 07/2013
2Irinotecan (Camptosar)FDA LinkGeneric
07/2013 - 08/2006
2Cisplatin (Platino)FDA LinkGeneric
01/2012 - 01/2003
2Messenger RNA (mRNA)IBA
01/2011 - 01/2007
2Valproic Acid (Depakote)FDA LinkGeneric
06/2008 - 07/2003
2Hormones (Hormone)IBA
05/2007 - 02/2006
2Estrogens (Estrogen)FDA Link
01/2007 - 07/2003
2Corticotropin-Releasing HormoneIBA
01/2007 - 02/2006
2Adenosine Diphosphate Ribose (ADP-Ribose)IBA
08/2006 - 02/2005
2Topoisomerase I InhibitorsIBA
08/2006 - 07/2005
2N3-methyladenineIBA
02/2005 - 07/2002
2methyl lexitropsinIBA
02/2005 - 03/2002
2Drug CombinationsIBA
10/2002 - 03/2002
1Neuroprotective AgentsIBA
12/2023
1Retinaldehyde (Retinal)IBA
12/2023
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2023
1Niacinamide (Nicotinamide)FDA LinkGeneric
12/2023

Therapy/Procedure

28Therapeutics
12/2023 - 02/2000
14Drug Therapy (Chemotherapy)
04/2024 - 07/2002
7Immunotherapy
11/2022 - 01/2019
3Oral Administration
11/2018 - 08/2006
2Radiotherapy
02/2017 - 01/2009